Precision Treatment Tools for Cardiovascular Diseases

This is a unique tool that can predict outcomes for specific cardiovascular disease groups and identify the best combination of medications to optimize their outcomes. It has been codeveloped and tested using our machine learning technology and clinical, demographics, biochemical exams and medications data from Syndesis Health (https://syndesis.com/) database.

PrecisionCHF Tool
The PrecisionCHF Tool is the Outcome Prediction and Precision Treatment of Congestive heart failure
 InSyBio Tool Manual
PrecisionHCM Tool
The PrecisionHCM Tool is the Outcome Prediction and Precision Treatment for Hypertrophic Cardiomyopathy Patients.
 InSyBio Tool Manual


Precision Chronic Pain Treatment Tools

The InSyBio Chronic Pain Precision Treatment Tools are used to stratify chronic pain patients into individuals who will benefit from topical analgesics treatments and select the most suitable non-opioid treatment formulation for them using as input a combination of demographics, clinical characteristics and other responses to a simple questionnaire.

In an effort to find a better alternative to the traditionally prescribed opioid analgesics, InSyBio worked in collaboration with Clarity Science LLC and developed a machine learning-based tool for predicting the response of chronic pain patients to 4 different non-opioid pain treatment formulations. This tool is capitalizing on InSyBio’s unique machine learning technology to develop machine learning models that are able to predict various response to treatment metrics (including pain severity and interference scales as well as reduction of total drugs) with an unprecedented accuracy.

The accuracy of these models in predicting the changes in the response to treatment metrics exceeded 82% for all metrics in a cohort of more than 600 patients while 98.1% of the participants which were classified as responders to non-opioid treatments presented substantial improvement in all metrics in a follow-up after 3-6 months from baseline.

@Topical Analgesics Tool
The InSyBio Chronic Pain Precision @Topical Analgesics Tool is a first-of-its-kind tool that is able to stratify chronic pain patients into individuals who will benefit from topical analgesics treatment and select the most suitable non-opioid treatment formulation for them using as input a combination of demographics, clinical characteristics and other responses to a simple questionnaire.
 InSyBio Tool Manual
@Salonpas Tool
The InSyBio Chronic Pain Precision Relief @Salonpas Tool is one of our InSyBio Chronic Pain Precision Treatment tools that are used to stratify chronic pain patients into individuals who will benefit from topical analgesics treatments and select the most suitable non-opioid treatment formulation for them using as input a combination of demographics, clinical characteristics and other responses to a simple questionnaire.
 InSyBio Tool Manual
@Kailo Tool
The InSyBio Chronic Pain Precision Relief @Kailo Tool is one of our InSyBio Chronic Pain Precision Treatment tools that are used to stratify chronic pain patients into individuals who will benefit from topical analgesics treatments and select the most suitable non-opioid treatment formulation for them using as input a combination of demographics, clinical characteristics and other responses to a simple questionnaire.
 InSyBio Tool Manual
@Upatras Osteoarthritis Tool

The InSyBio Upatras Osteoarthritis Tool is one of our InSyBio Chronic Pain Precision Treatment tools that are used to stratify chronic pain patients into individuals who will benefit from topical analgesics treatments and select the most suitable non-opioid treatment formulation for them using as input a combination of demographics, clinical characteristics and other responses to a simple questionnaire.

 InSyBio Tool Manual

InSyBio Precision Chronic Pain Treatment Tool has been developed for the US population, and is mainly intended for use in the US. All medical decisions need to be taken by a patient in consultation with their doctor. The authors and the sponsors of this tool accept no responsibility for clinical use or misuse of the machine learning empowered prognostic scores or any other detail displayed in our tool.

@Topical Analgesics Patient Tool
The InSyBio Chronic Pain Precision @Topical Analgesics Tool is a first-of-its-kind tool that is able to stratify chronic pain patients into individuals who will benefit from topical analgesics treatment and select the most suitable non-opioid treatment formulation for them using as input a combination of demographics, clinical characteristics and other responses to a simple questionnaire.
 InSyBio Tool Manual
@Salonpas Patient Tool
The InSyBio Chronic Pain Precision Relief @Salonpas Tool is one of our InSyBio Chronic Pain Precision Treatment tools that are used to stratify chronic pain patients into individuals who will benefit from topical analgesics treatments and select the most suitable non-opioid treatment formulation for them using as input a combination of demographics, clinical characteristics and other responses to a simple questionnaire.
 InSyBio Tool Manual
@Kailo Patient Tool
The InSyBio Chronic Pain Precision Relief @Kailo Tool is one of our InSyBio Chronic Pain Precision Treatment tools that are used to stratify chronic pain patients into individuals who will benefit from topical analgesics treatments and select the most suitable non-opioid treatment formulation for them using as input a combination of demographics, clinical characteristics and other responses to a simple questionnaire.
 InSyBio Tool Manual
@Upatras Osteoarthritis Patient Tool
The InSyBio Upatras Osteoarthritis Tool is one of our InSyBio Chronic Pain Precision Treatment tools that are used to stratify chronic pain patients into individuals who will benefit from topical analgesics treatments and select the most suitable non-opioid treatment formulation for them using as input a combination of demographics, clinical characteristics and other responses to a simple questionnaire.
 InSyBio Tool Manual


Heuristic Optimization of Scaffold Design

Scaffold Design Optimization and Prediction Tool
Our tool combines genetic algorithms with machine learning models to support scaffold design optimization and prediction. This advanced toolkit allows users to achieve desired structural characteristics within random porous scaffolds, making it an ideal solution for biomedical and materials engineering applications. Designed in alignment with osteonethorizon.com, it is compatible with multiple bioreactors designs due to its focus on universal scaffold design parameters.


Metabolic AI™